What:

The goal of Q2M is to bridge Harvard Medical School’s Department of Systems Biology with the clinical trainees at the Harvard affiliated hospitals.  Each month, we will have an afternoon seminar illustrating how high priority problems in medicine can be tackled using quantitative and systematic approaches.  We will present examples of the application of mathematical and analytic models to disease and physiology with relevance to the practice of medicine.  Topics include rigorous, analytic studies that lead to clear, quantifiable, and falsifiable predictions regarding specific human diseases or physiology.

When and Where:

The seminar will take place on the second Thursday of each month 4-6 pm in the Cannon Room at the Harvard Medical School quadrangle.  Q2M will be launched in April 2008 with a two-month hiatus in July and August as well as a December break.

Schedule:

2008
April	10	James J. Collins, PhD	“Tuning up your patients: noise-enhanced human function”
May	8	Jeffrey Fredberg, PhD	“Frozen objects: small airways, big breaths, and asthma”
June	12	Local Conference	“Systems Biology of Human Disease”
July		Summer Break	Summer Break
August		Summer Break	Summer Break
September	11	Sally M. Blower, PhD	“Modeling clinical trials & public health interventions”
October	2	Mark Daly, PhD	"Genetic predictors of common human disease"
November	13	William F. Crowley, MD	“Pulsatile hormone secretion”
December		December Break	December Break
2009
January	8	TBA	TBA
February	12	Richard Bergman, MD	“Dynamics of glucose homeostasis”
March	12	TBA	TBA
April	2	TBA	TBA
May	14	Martin Nowak, PhD	“Somatic evolutionary dynamics of cancer”
June	11	Todd Golub, MD	“Connecting genes, diseases, and drugs.”

Organizers:

Q2M is directed by Vamsi Mootha, Assistant Professor of Systems Biology at HMS, and co-directed by Ramy Arnaout and John Higgins, both Clinical Fellows in Pathology at Brigham and Women’s Hospital.

Contact: